Every Company Is Now An AI Wrapper So GTM Is The New Moat

The frontier model is a commodity. The companies winning are the ones that own distribution, and venture capital is paying up for it.

AbbVie’s $11 Billion Immunology Bet

In this week’s edition of InnovationRx, we look at AbbVie’s new megadeal, an agentic AI startup saving Medicare $2 million a week, how new student loan rules could degrade healthcare and more.

Agentic Commerce Needs Open Infrastructure To Scale

Adyen, Stripe, Visa, Mastercard, Google UCP, PayPal, and crypto-native challengers mapped by protocol reach and merchant control, after OpenAI’s checkout collapse handed Google the standards race.

AI Is Rewriting Mortgage Origination And VCs Are Starting To Notice

Independent mortgage banks lost $1,056 per loan in 2023. Now a new wave of AI-native startups, from Copperlane to Blend Labs, is targeting the $11,000 cost to originate a single mortgage. Here is how the competitive map is taking shape.

NEA’s Tiffany Luck says enterprises are still figuring out their AI ROI

Tokenmaxxing was the hottest trend in Silicon Valley earlier this year, with CEOs encouraging employees to push AI usage as far as it would go. Then the bill came due. Uber reportedly blew through its annual AI budget in a…

AI Platform Wars Are Moving Into Workflows Where Billions Are At Stake

AI’s next platform war is about who controls the workflows where intent, context, and execution converge; and which companies will capture platform economics versus being compressed into infrastructure.

In The Stablecoin Race, Noah Is Selling The Shovels

The $179 trillion cross-border payments market still operates on outdated infrastructure, creating a massive opportunity for disruption.

SpaceX IPO Lines Up $230 Billion Windfall For Peter Thiel And Other Musk Backers

SpaceX’s monster initial public offering could deliver massive gains for some of Elon Musk’s earliest and most loyal backers like Founders Fund, Valor Equity Partners, and DFJ Growth.

SpaceX Investments Now Dominate The 10 Best VC Checks Of All Time

Venture capitalists now have stakes worth hundreds of billions thanks to the record-breaking SpaceX IPO. These are the most lucrative VC checks ever.

The New Billionaire Bet Isn’t AI — It’s Longevity Biotech

As AI transforms biology, longevity startups are attracting investors, advancing toward clinical milestones, and reshaping the future of aging research.