What’s next for IVF
What’s next for IVF

Forty-eight years ago this July, Louise Joy Brown became the world’s first person born with the help of in vitro fertilization. Millions more IVF babies have entered the world since then. And that’s partly thanks to advances in technology that have made IVF safer and more effective. But it’s still not perfect. The process can…

Tailoring AI solutions for health care needs
Tailoring AI solutions for health care needs

The AI market is full of big promises of grand transformation. Health care is a prime target for those promises, beset as it is by financial pressures, labor shortages, and the growing burden of caring for an aging population. AI developers are targeting functions that vary widely, from curing cancer and performing surgery to streamlining…

Health-care AI is here. We don’t know if it actually helps patients.

I don’t need to tell you that AI is everywhere. Or that it is being used, increasingly, in hospitals. Doctors are using AI to help them with notetaking. AI-based tools are trawling through patient records, flagging people who may require certain support or treatments. They are also used to interpret medical exam results and X-rays. A…

Colossal Biosciences said it cloned red wolves. Is it for real?
Colossal Biosciences said it cloned red wolves. Is it for real?

If you want to capture something wolflike, it’s best to embark before dawn. So on a morning this January, with the eastern horizon still pink-hued, I drove with two young scientists into a blanket of fog. Forty miles to the west, the industrial sprawl of Houston spawned a golden glow. Tanner Broussard’s old Toyota Tacoma…

No one’s sure if synthetic mirror life will kill us all
No one’s sure if synthetic mirror life will kill us all

For four days in February 2019, some 30 synthetic biologists and ethicists hunkered down at a conference center in Northern Virginia to brainstorm high-risk, cutting-­edge, irresistibly exciting ideas that the National Science Foundation should fund. By the end of the meeting, they’d landed on a compelling contender: making “mirror” bacteria. Should they come to be,…

What’s in a name? Moderna’s “vaccine” vs. “therapy” dilemma

Is it the Department of Defense or the Department of War? The Gulf of Mexico or the Gulf of America? A vaccine—or an “individualized neoantigen treatment”? That’s the Trump-era vocabulary paradox facing Moderna, the covid-19 shot maker whose plans for next-generation mRNA vaccines against flus and emerging pathogens have been dashed by vaccine skeptics in…

Inside the stealthy startup that pitched brainless human clones
Inside the stealthy startup that pitched brainless human clones

After operating in secrecy for years, a startup company called R3 Bio, in Richmond, California, suddenly shared details about its work last week—saying it had raised money to create nonsentient monkey “organ sacks” as an alternative to animal testing. In an interview with Wired, R3 listed three investors: billionaire Tim Draper, the Singapore-based fund Immortal…

A woman’s uterus has been kept alive outside the body for the first time
A woman’s uterus has been kept alive outside the body for the first time

“Think of this as a human body,” says Javier González. In front of me is essentially a metal box on wheels. Standing at around a meter in height, it reminds me of a stainless-steel counter in a restaurant kitchen. It is covered in flexible plastic tubing—which act as veins and arteries—connecting a series of transparent…

Here’s why some people choose cryonics to store their bodies and brains after death

This week I reported on some rather unusual research that focuses on the brain of L. Stephen Coles. Coles was a gerontologist who died from pancreatic cancer in 2014. He had spent the latter part of his career specializing in human longevity. And before he died, he decided to have his brain preserved by a…

This scientist rewarmed and studied pieces of his friend’s cryopreserved brain

L. Stephen Coles’s brain sits cushioned in a vat at a storage facility in Arizona. It has been held there at a temperature of around −146 degrees °C for over a decade, largely undisturbed. That is, apart from the time, a little over a year ago, when scientists slowly lifted the brain to take photos…